Applied Physiology in Noninvasive Mechanical Ventilation: Key Practical Insights

Antonio M. Esquinas, MD PhD FCCP

Director, International School of Noninvasive Ventilation
staff physician, Intensive Care Unit
Hospital Morales Meseguer
Murcia, Spain

Now accepting pre-orders for February 2021 publication.

Applied Physiology in Noninvasive Mechanical Ventilation: Key Practical Insights explains the implications of lung physiology — lung mechanics, gas exchange — on noninvasive mechanical ventilation under a variety of clinical conditions.

Focused on understanding how lung physiology interacts with noninvasive ventilation, this book will be an excellent reference for pulmonologists, anesthesiologists, critical care physicians, and emergency medicine physicians in their treatment and care of patients with acute and chronic respiratory disorders.

The book’s 67 chapters are divided into six sections that take the reader through these topics:

(1) pulmonary physiology as it interacts with noninvasive mechanical ventilation (NIV), and physiology of the respiratory muscles, structure and function of lung mechanics;

(2) the interaction of lung physiology with positive pressure, extrapulmonary response (hemodynamic-ventilation interactions);

(3) gas exchange and applied physiology during NIV;

(4) interactions of lung mechanics with NIV in terms of pressure, volume, flow, monitoring, testing of pulmonary function;

(5) NIV technology: interface and mechanical ventilators, patient-ventilator synchrony, ventilatory modes, monitoring patient-ventilator interaction;

(6) physiopathologic perspective on clinical applications of NIV.

Preface Contributors PART 1. PULMONARY PHYSIOLOGY APPLIED FOR NONINVASIVE VENTILATION Section 1. Breathing Pattern and Lung Interactions Chapter 1. Spontaneous respiratory breathing: physiology by Henry B. Alanez Saavedra, Gabriel J. Moreno González Chapter 2. Breathing patterns and neurologic response: loop neurological-lung mechanics interactions by Maria Alvarenga Santos, Antonio M. Esquinas Chapter 3. Breathing pattern classifications: apnea, hypopnea, and tachipnea by Gonzalo Segrelles Calvo, Estefanía Llopis, Daniel López-Padilla, Enrique Zamora Chapter 4. Pulmonary-biochemical and physical reflex interactions by Nídia Nanci Pestana Caires Section 2. Physiology of Respiratory Muscles Chapter 5. Respiratory muscle weakness and fatigue: concept and clinical implications by Gaetano Scaramuzzo, Corrado Mollica, Savino Spadaro Chapter 6. Respiratory accessory muscular inspiratory function: clinical evaluations and implications by Laura Anguela Calvet, Juan C. Lopez-Delgado Chapter 7. Respiratory expiratory muscular function: clinical evaluations and implications by Irene Nieto Codesido, Pedro J. Marcos Chapter 8. Respiratory muscle performance: evaluation and monitoring; key determinants by Elvira-Markela Antonogiannaki, Michail Fanaridis, Eumorphia Kondili Chapter 9. Summary and key practical tools to assess muscular response pattern response by Olga Moreno Romero, Alberto Fernández Carmona, Ana Maria Perez Bailon Section 3. Lung Mechanics, Compliance, and Resistance Chapter 10. Thorax: the structure-function by Luca Salvatore De Santo, Angelo Ausania, Carlo Zebele Chapter 11. Compliance and applied physiology for noninvasive ventilation: function and anatomical determinants by Carmen Hernandez Chapter 12. Airways resistance: function and anatomical determinants by Stavros Tryfon Chapter 13. Restrictive respiratory failure: applied physiology and clinical implications by Dimitrios Lagonidis PART 2. POSITIVE PRESSURE AND INTERACTION WITH LUNG PHYSIOLOGY Section 1. Positive Pressure, Physics, and Implications Chapter 14. Interactions: positive pressure ventilation and lung physiology by Jakob Wittenstein Chapter 15. Negative noninvasive ventilation by Umberto Vincenzi Chapter 16. Physiological interactions of high flow nasal cannula therapy by Pedro Silva Santos Section 2. Extrapulmonary Response: Hemodynamic-Ventilation Interactions Chapter 17. Preload and left ventricular workload: cardiac output interactions by Lorena Olivencia Peña, Juan José Cruz Rueda, and Alberto Fernandez Carmona Chapter 18. Noninvasive ventilation and hemodynamic interactions by Eylem Tuncay, Gökay Güngör Chapter 19. Summary and key practical tools to assess hemodynamic response to noninvasive ventilation by Jacobo Bacariza PART 3. GAS EXCHANGE AND APPLIED PHYSIOLOGY DURING NONINVASIVE VENTILATION Chapter 20. Gas exchange physiology by Paolo Banfi. Chapter 21. Hypoxemic conditions: Fi02/oxygenation, patterns of response, and classifications by Chinmaya Panda, Subrata Singha Chapter 22. Hypercapnic conditions: patterns of response, classifications, and rebreathing by Juan José Cruz Rueda, Lorena Olivencia Peña, Alberto Iglesias Santiago Chapter 23. Practical tools to assess the impact of noninvasive ventilation on gas exchange by Habib Mohammad Reazaul Karim, Pradipta Bhakta PART 4. INTERACTIONS OF LUNG MECHANICS WITH NONINVASIVE VENTILATION Section 1. Pressure, Volume, and Flow Chapter 24. Lung mechanics and airways: implications for clinical practical decisions by Burhan Sami Kalın, Gül Gursel Chapter 25. Lung mechanics and compliance by Preet Mohinder Singh, Amit K. Malviya Section 2. NIV Monitoring Chapter 26. Monitoring lung function: pressure, volume, and flow; basic curves; interpretation and key determinants by Teresa Diaz de Teran, Antonello Nicolini, Paolo Banfi Chapter 27. Expiratory volume: concept and clinical implications by Oya Baydar Toprak, Ezgi Özyilmaz Saraç Chapter 28. Pulse oximetry and noninvasive ventilation applications by Antonio Pisano, Diana Di Fraja, Manuela Angelone Chapter 29. Transcutaneous capnography tracings and noninvasive ventilation by Müge Aydoğdu Chapter 30. Diaphragm electrical activity and implications during noninvasive ventilation by Savino Spadaro, Marta Lazzeri, Alberto Fogagnolo Chapter 31. Electrical impedance tomography and radiologic CT scan evaluation during noninvasive ventilation by Thierry Hernández-Gilsoul Section 3. Pulmonary Function Test Chapter 32. Lung volumes and vital capacity: measurement, determinants, and implications by Alberto Fernandez Carmona Chapter 33. Cough and flow measurement: measurement, determinants, and implications during noninvasive ventilation by Alberto Fernandez Carmona PART 5. NONINVASIVE VENTILATION TECHNOLOGY Section 1. Interface and Mechanical Ventilators Chapter 34. Implications of ventilator interface and lung physiology by Antonio M. Esquinas, Giuseppe Fiorentino, and Anna Annunziata Chapter 35. Classification of noninvasive ventilators: technical and practical issues by Raffaele Scala Chapter 36. Noninvasive ventilator software: estimating ventilation, tidal volume, and leaks by Manel Luján Torné Chapter 37. Critical care mechanical ventilators: accuracy-positive pressure, flow measurements, tidal volume, leak measurements by Antonio Esquinas, Habib Mohammad Reazaul Karim, Subrata Singha Chapter 38. Effects of leak compensation on patient-ventilator synchrony by Hadil A. Al Otair, Ahmed S. BaHammam Section 2. Patient-Ventilator Synchrony and Ventilatory Modes Chapter 39. Ventilator-patient synchronization during noninvasive ventilation by Zbigniew Szkulmowski Chapter 40. Pressure support ventilation by Alberto Bordo, Enrico Perretta Chapter 41. Inspiratory positive airway pressure: concept, clinical implications, and technology by Bushra Mina, Oki Ishikawa Chapter 42. Expiratory positive airway pressure: concept, clinical implications, and technology by Karthik Seetharam, Antonio M. Esquinas, Bushra Mina Chapter 43. Noninvasive ventilation ramp option on pressure support; lung-patient interactions by Gonzalo Segrelles Calvo, Néstor Luis Rodríguez Meleán, Estefanía Llopis Chapter 44. Neurally adjusted noninvasive ventilation by Ilaria Sguazzotti, Gianmaria Cammarota, Carlo Olivieri Chapter 45. Use of noninvasive ventilation with adaptive servo ventilation: practical impliations by Killen H. Briones-Claudett Chapter 46. CPAP devices: algorithms and equipment by Vânia Fernandes, Margarida Alonso Chapter 47. CPAP and auto-CPAP mode in obstructive sleep apnea by Paola Pierucci Chapter 48. Key determinants of noninvasive ventilation withdrawal by Bushra Mina Section 3. Monitoring Patient-Ventilator Interaction Chapter 49. Monitoring patient-ventilator interactions by Emine Aksoy, Zuhal Karakurt Chapter 50. Patient ventilator asynchrony: frequency and types by Lars-Olav Harnisch, Onnen Moerer Chapter 51. Patient ventilator asynchrony: clinical conditions and pathophysiological disease by Kamil Inci, MD, Gül Gürsel, MD Chapter 52. Auto positive expiratory pressure: concepts and implications in noninvasive ventilation by Serena Wei J. Hsia, Catherine S. Sassoon Chapter 53. Impact of inspiratory positive airway pressure on patient ventilator asynchrony; key practical recommendations by M.L. Duiverman, S. Van der Leest Chapter 54. Impact of expiratory positive airway pressure on patient ventilator asynchrony; key practical recommendations by Milind P. Sovani Chapter 55. Asynchrony and noninvasive ventilation: summary of clinical and bench studies by Dhruva Chaudhry Chapter 56. Experience of the medical team and patient-ventilator asynchrony, by Lindsay Lief, Lourdes Sanso Chapter 57. Tools and key practical insights for noninvasive ventilation response and evaluation; concept and implications of early and late failure by Guy W. Soo Hoo PART 6. Basic Clinical Applications for Noninvasive Ventilation, Physiopathology Perspective Chapter 58. Acute and chronic hypercapnic respiratory failure: determinants and evaluation by Krystel Maisterra Santos, Juan C. Lopez-Delgado Chapter 59. Acute hypoxemic respiratory failure by Isaac Chouris, Dimitrios Lagonidis Chapter 60. Physiology of noninvasive ventilation in acute cardiac failure by Zehra Hatipoğlu Chapter 61. Physiology of noninvasive ventilation in heart failure in postoperative respiratory failure by Athanasia Proklou, Eleni Diamantaki, Emmanouil Pediaditis, Eumorfia Kondili Chapter 62. Physiology of noninvasive ventilation in heart failure in obesity hypoventilation by Preet Mohinder Singh, Basavaraj Ankalagi Chapter 63. Diagnosis and technical aspects of noninvasive positive pressure ventilation in hypoventilatıon syndromes by Uğur Özdemir, Gül Gürse Chapter 64. Physiology and noninvasive ventilation in sleep related hypoventilation syndromes by Claudio De Michelis Chapter 65. Noninvasive ventilation in long-term applications by Francesco Balbi, Alberto Bordo, Claudio De Michelis Chapter 66. Lung physiology during ventilatory complementary technologies: aerosoltherapy, humidification, and cough assisted by Soraya Jodra Sanchez, Jair José Rauseo López Chapter 67. Noninvasive ventilation in pulmonary rehabilitation and lung physiology in exercise by Virginia Guevara Velasco, Milagros Rosales Dedios

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Book Details

400 pages est.


8.5″ x 11″


Pulmonologists, anesthesiologists, respiratory therapists, critical care and emergency physicians and nurses

ISBN 9781607953005