Craniofacial Embryogenetics and Development

Geoffrey H. Sperber, BSc (Hons) BDS MS PhD FICD, Dr Med Dent (Honoris Causa), For Assoc Roy Soc S Af

Faculty of Medicine and Dentistry
University of Alberta
Edmonton, Alberta, Canada

Steven M. Sperber, MSc PhD DABMGG FACMG

Director, Molecular Diagnostics Laboratory
Department of Pathology and Laboratory Medicine
SUNY Upstate Medical University
Syracuse, New York

The field of embryology has experienced a period of explosive growth since the previous edition of this book was published nearly a decade ago. The insights of genetic expression in determining the unfolding of the embryonic layers have revolutionized our understanding of some of the mechanisms of embryogenesis.

As implied by the title of the third edition, Craniofacial Embryogenetics and Development, genetics is linked with embryology in this text. Virtually all embryological development has an underlying genetic component, and the basic science of genetics is the key in uncovering the many mysteries of embryogenesis. The tools of molecular genetics have provided insights into developmental mechanisms that allow us the ability to identify transient regions of genetic expression patterns.

Unraveling the precise biochemical and mechanical interactions of discrete regions in the unfolding embryonic components remains a dauntingly complex challenge to understanding the conversion of the genome into the phenome. The addition of genetic information gleaned from other mammalian species might aid in dissecting human embryology into comprehensible components to understand normal and abnormal development. The third edition of Craniofacial Embryogenetics and Development is dedicated to this objective.

Key Features:

  • Provides clinicians with a basic background for assessing and treating craniofacial anomalies.
  • Describes recent technical advances in optical projection tomography, photoacoustic and 3D imaging, small-angle X-ray scattered (SAXS) tomography and morphometrics and their impact on embryogenetics.




Preface to Previous Edition

SECTION I. General Embryology

CHAPTER 1: Mechanisms of Embryology
CHAPTER 2: Early Embryonic Development
CHAPTER 3: Early Orofacial Development
CHAPTER 4: Pharyngeal Arches
CHAPTER 5: Pharyngeal Pouches and Pharyngeal Grooves
CHAPTER 6: Bone Development and Growth

SECTION II. Craniofacial Development

CHAPTER 7: Calvaria
CHAPTER 8: Cranial Base
CHAPTER 9: Facial Skeleton
CHAPTER 10: Palate
CHAPTER 11: Paranasal Sinuses
CHAPTER 12: Mandible
CHAPTER 13: Temporomandibular Joint
CHAPTER 14: Skull Growth: Sutures and Cephalometrics
CHAPTER 15: Tongue and Tonsils
CHAPTER 16: Salivary Glands
CHAPTER 17: Muscle Development
CHAPTER 18: Special Sense Organs
CHAPTER 19: Development of the Dentition (Odontogenesis)
CHAPTER 20: Craniofacial Disorders with Known Single Gene Mutations



A book review in the June 2019 issue of the American Journal of Orthodontics and Dentofacial OrthopedicsAJO-DO book review

A book review published March 11, 2019 in the European Journal of Orthodontics: EJO book review

$65.95 Add To Cart
Book Details

272 pages


8.5 in. x 11 in.

Publication Date October 2018

Embryologists, anatomists, oral and maxillofacial surgeons, facial plastic and cosmetic surgeons, otolaryngologists, prosthodontists, orthodontists, dentists, neonatal pediatricians, speech pathologists, teratologists,

ISBN 9781607952824
eISBN 9781607959489