Molecular Imaging: Principles and Practice
In the 21st century, the field of molecular imaging of living subjects has evolved considerably and has seen spectacular advances in chemistry, engineering, and biomedical applications. Comprehensive molecular imaging centers have been established in the US, Europe, and Asia and are increasingly integrated into basic sciences and translational networks.
New investigators, collaborators, and students drawn into this multidisciplinary field have often expressed the desire and need for an authoritative textbook. The editors designed Molecular Imaging: Principles and Practice precisely to fill the need for an authoritative, effective resource with contributions from 160 leading authors.
Given the multidisciplinary nature of the field, the information is organized into six logical, illustrated sections. See the Table of Contents tab below for section and chapter titles.
Molecular Imaging: Principles and Practice received a 97 Doody’s Review score.
Part I: Molecular Imaging Technologies
Chapter 1 General Principles of Molecular Imaging
Chapter 2 Imaging of Structure and Function with PET/CT
Chapter 3 PET/MRI
Chapter 4 SPECT and SPECT/CT
Chapter 5 Principles of Micro X-ray Computed Tomography
Chapter 6 Small Animal SPECT, SPECT/CT, and SPECT/MRI
Chapter 7 Instrumentation and Methods to Combine Small Animal PET with Other Imaging Modalities
Chapter 8 Functional Imaging Using Bioluminescent Imaging
Chapter 9 Optical Multimodality Technologies
Chapter 10 Fiber Optic Fluorescence Imaging
Chapter 11 Fluorescence Tomography
Chapter 12 Endomicroscopy
Chapter 13 Intravital Microscopy
Chapter 14 Diffuse Optical Tomography and Spectroscopy
Chapter 15 Ultrasound
Chapter 16 Molecular Photoacoustic Tomography
Chapter 17 Optical Projection Tomography
Chapter 18 Potential Roles for Retrospective Registration in Molecular Imaging
Part II: Chemistry of Molecular Imaging
Chapter 19 Chemistry of Molecular Imaging: An Overview
Chapter 20 Radiochemistry of PET
Chapter 21 Radiochemistry of SPECT: Examples of 99MTc and 111In Complexes
Chapter 22 Nanochemistry for Molecular Imaging
Chapter 23 Newer Bioconjugation Methods
Chapter 24 Targeted Antibodies and Peptides
Chapter 25 Hyperpolarized 13C Magnetic Resonance Imaging – Principles and Applications
Chapter 26 Magnetic Resonance Imaging Agents
Chapter 27 Optical Imaging Agents
Chapter 28 Ultrasound Contrast Agents
Chapter 29 Multimodality Agents
Chapter 30 “Click Chemistry”: Applications to Molecular Imaging
Chapter 31 The “One-Bead-One-Compound” Combinatorial Approach to Identifying Molecular Imaging Probes
Chapter 32 Chemical Biology Approaches to Molecular Imaging
Chapter 33 Theranostics: Agents for Diagnosis and Therapy
Chapter 34 Magnetic Nanoparticles
Chapter 35 Fluorocarbon Agents for Quantitative Multimodal Molecular Imaging and Targeted Therapeutics
Chapter 36 Aptamers for Molecular Imaging
Chapter 37 Nonclinical Product Developmental Strategies, Safety Considerations, and Toxicity Profiles of Medical Imaging and Radiopharmaceutical Products
Part III: Molecular Imaging in Cell & Molecular Biology
Chapter 38 Overview of Molecular and Cell Biology
Chapter 39 Systems Biology
Chapter 40 Protein Engineering for Molecular Imaging
Chapter 41 Phage Display for Imaging Agent Development
Chapter 42 Molecular Imaging of Gene Therapy
Chapter 43 Developing Diagnostic and Therapeutic Viral Vectors
Chapter 44 Cell Voyeurism Using Magnetic Resonance Imaging
Chapter 45 Tumor Vasculature
Chapter 46 Imaging Hypoxia
Chapter 47 Molecular Imaging of Protein-Protein Interactions
Chapter 48 Fluorescence Readouts of Biochemistry in Live Cells and Organisms
Chapter 49 Imaging of Signaling Pathways
Part IV: Applications of Molecular Imaging
Oncology:
Chapter 50 Molecular and Functional Imaging of the Tumor Microenvironment
Chapter 51 Novel MR and PET Imaging in the RT Planning and Assessment of Response of Malignant Gliomas
Chapter 52 PET Diagnosis and Response Monitoring in Oncology
Chapter 53 Magnetic Resonance Spectroscopy Treatment Response and Detection
Chapter 54 Diffusion MRI: A Biomarker for Early Cancer Treatment Response Assessment
Cardiovascular:
Chapter 55 Myocardial Metabolism
Chapter 56 Congestive Heart Failure
Chapter 57 Molecular Imaging of Atherosclerosis
Chapter 58 Thrombosis and Embolism
Chapter 59 Molecular Imaging of Stem Cells in Myocardial Infarction
CNS:
Chapter 60 Central Nervous System Molecular Imaging
Chapter 61 Neuroreceptor Imaging: Applications, Advances, and Limitations
Chapter 62 PET and SPET Imaging of Neurodegenerative Diseases
Autoimmune/Immunology:
Chapter 63 Molecular Imaging of Autoimmune Diseases
Chapter 64 Rheumatoid Arthritis
Chapter 65 Autoimmune Diabetes
Chapter 66 Imaging in Asthma
Part V: Molecular Imaging in Drug Evaluation
Chapter 67 Molecular and Functional Imaging in Drug Development
Chapter 68 PET Imaging Cancer Clinical Trials
Chapter 69 MR Imaging in Clinical Trials
Chapter 70 Imaging of Gene Therapy: Basis and Clinical Trials
Part VI: Other
Chapter 71 Visualization
Chapter 72 Quantification of Radiotracer Uptake into Tissue
Chapter 73 Mining Genomic Data for Molecular Imaging Targets
Chapter 74 Pharmacokinetic Modeling
Chapter 75 Cost-Effectiveness Analysis/Economics of Probe Development
Chapter 76 Regulatory and Reimbursement Process for Imaging Agents and Devices
Index