Sarcoma Oncology: A Multidisciplinary Approach

Raphael E. Pollock, MD PhD

Professor and Director
Division of Surgical Oncology

Vice Chairman for Clinical Affairs
Department of Surgery

Surgeon in Chief, James Comprehensive Cancer Center
Surgeon in Chief, The Ohio State University Health System
Physician, FGP-Surgical Oncology

The Ohio State University

Columbus, Ohio

R. Lor Randall, MD FACS

Professor of Sarcoma Services
man Cancer Institute and
Primary Children’s Medical Center
Professor of Orthopaedics
The L.B. & Olive S. Young Endowed Chair for Cancer Research
University of Utah

Salt Lake City, Utah

Brian O'Sullivan, MB Bch BAO FRCPC

Departments of Radiation Oncology
and Otolaryngology
Associate Director
Radiation Medicine Program

Princess Margaret Hospital

Toronto, Ontario, Canada

Pre-publication orders will be taken.

Sarcoma Oncology: A Multidisciplinary Approach is a comprehensive textbook that addresses the entire spectrum of the subject from epidemiology to laboratory research in the biology of sarcomas.

Chapters contributed by an international group of highly regarded specialists cover the epidemiology and pathology of sarcomas; diagnostic imaging and biopsy techniques; staging and prognosis: surgery of sarcomas in extremity soft tissue, abdominal wall and trunk, and skeletal bone; hyperthermia in sarcoma treatment; isolated limb perfusion; surgery for metastases; reconstructive surgery; radiation therapy; systemic chemotherapy; multidisciplinary care; treatment-induced sarcoma; pain management in sarcoma; and basic research including molecular biology and mouse models.

Section 1. Overview: Epidemiology, Pathology, Imaging, Staging, and Prognosis
Ch 1 Environmental and inherited risk factors in Sarcomas
Ch 2 Introduction to Pathology
Ch 3 Pathology of STS and Molecular Diagnostics
Ch 4 Pathology of Bone Sarcoma
Ch 5 Bone and Soft Tissue Tumors: Contemporary Imaging
Ch 6 Metabolic and Molecular Imaging of Mesenchymal Tumors
Ch 7 RECIST vs. Choi assessment of response
Ch 8 Biopsy Techniques
Ch 9 Staging systems/prognostic factors; Nomograms and other models

Section 2. Sarcoma Treatment Modalities
Ch 10 Purpose and Role: Relationship to Other Modalities
Ch 11 Types of resection and anatomic considerations; margin issues
Ch 12 Surgery of abdominal wall and trunk sarcoma
Ch 13 Surgical Management of Upper Extremity Bone Sarcomas
Ch 14 Surgical Management of Lower Extremity Bone Sarcomas
Ch 15 Surgical Management of Spinal Sarcoma
Ch 16 Surgical treatment of pelvic bone sarcomas
Ch 17 Isolated limb perfusion in sarcoma
Ch 18 Surgical treatment of sarcomatous lung metastases
Ch 19 Composite tissue reconstruction after sarcoma resection
Ch 20 External beam/Intensity Modulated Radiotherapy
Ch 21 Intraoperative irradiation
Ch 22 Soft Tissue Sarcoma brachytherapy
Ch 23 Particle Beam Therapy for Sarcoma
Ch 24 Hyperthermia in sarcoma treatment
Ch 25 Chemotherapy for Soft Tissue Sarcomas: Contemporary Approaches
Ch 26 Personalized molecular therapeutics
Ch 27 Sarcomas of the Breast
Ch 28 Sarcomas of the Head and Neck

Section 3. Multidisciplinary Care
Ch 29 Genitourinary Sarcomas
Ch 30 Retroperitoneal Sarcoma and Relapse
Ch 31 Sarcoma of Heart and Great Vessels
Ch 32 Chest Wall Sarcoma

Section 4. Specific Histologies
Ch 33 Desmoid Tumors: A Treatment Algorithm According to Biological Behavior
Ch 34 Dermatofibrosarcoma Protuberans
Ch 35 Kaposi’s Sarcoma
Ch 36 GIST: Contemporary Understanding and Management
Ch 37 Biology of GIST
Ch 38 Medical Management and Treatment of Recurrent GIST
Ch 39 Surgical Management of GIST
Ch 40 Malignant peripheral nerve sheath sarcoma
Ch 41 Osteosarcoma
Ch 42 Ewing sarcoma family of tumors
Ch 43 Chondrosarcoma
Ch 44 Chordoma
Ch 45 Rhabdomyosarcoma
Ch 46 Liposarcoma
Ch 47 Leiomyosarcoma
Ch 48 Malignant fibrous histiocytoma
Ch 49 Angiosarcoma
Ch 50 Hemangioendothelioma
Ch 51 Solitary fibrous tumors in the 21st century: a clinical and pathologic update
Ch 52 Clear cell sarcoma
Ch 53 Alveolar soft part sarcoma
Ch 54 Synovial sarcoma
Ch 55 Epithelioid sarcoma

Section 5. Relapsed Sarcoma
Ch 56 Treatment-Induced Sarcoma
Ch 57 Locally Recurrent Extremity Soft Tissue Sarcoma

Section 6. Additional Considerations
Ch 58 Chemotherapy for Palliation
Ch 59 Medical Palliation
Ch 60 Surgical Palliation
Ch 61 Cost-effective Follow-up
Ch 62 Sarcoma Survivorship
Ch 63 Long-term Complications Associated with Chemotherapy
Ch 64 Long-term Complications Associated with Radiation Therapy in Soft Tissue Sarcoma Management
Ch 65 Functional Assessment and Quality of Life in Soft Tissue Sarcomas
Ch 66 Patient Advocacy Issues in Sarcoma
Ch 67 Sarcoma and the Internet

Section 7. Laboratory Research
Ch 68 Tumor-Initiating (Stem) Cells
Ch 69 Genetically Engineered Mouse Models of Sarcoma
Ch 70 Molecular Profiling of Sarcomas
Ch 71 Recent Advances in the Characterization of Mesenchymal Tumors: From Sarcoma Genomics to Targeted Therapies
Ch 72 Telomere Maintenance Mechanisms
Ch 73 Tumor Microenvironment Crosstalk

$225.00 Add To Cart
Book Details

700 pages


8.5 in. x 11 in.

Publication Date December 2018

Oncologists, histologists, pathologists, radiologists, surgeons

ISBN 9781607950172